{"id":1372992,"date":"2023-05-09T08:22:59","date_gmt":"2023-05-09T06:22:59","guid":{"rendered":"https:\/\/dev.dnaera.com\/cs\/?p=1372992"},"modified":"2023-07-24T10:21:16","modified_gmt":"2023-07-24T08:21:16","slug":"skryte-pouto-matka-dite","status":"publish","type":"post","link":"https:\/\/dev.dnaera.com\/cs\/blog\/skryte-pouto-matka-dite\/","title":{"rendered":"Skryt\u00e9 pouto, kter\u00e9 spojuje matku a d\u00edt\u011b ne\u010dekan\u00fdm zp\u016fsobem"},"content":{"rendered":"\n

O tom, \u017ee \u017eeny p\u0159ed\u00e1vaj\u00ed sv\u00e9mu d\u00edt\u011bti p\u0159ibli\u017en\u011b 50 % jeho DNA, jste u\u017e jist\u011b sly\u0161eli. M\u00e9n\u011b zn\u00e1m\u00e9, ale ne a\u017e tak p\u0159ekvapiv\u00e9 je, \u017ee bu\u0148ky z t\u011bla matky se v mal\u00e9 m\u00ed\u0159e dost\u00e1vaj\u00ed b\u011bhem jeho v\u00fdvoje do t\u011bla d\u00edt\u011bte. O \u010dem jste v\u0161ak je\u0161t\u011b asi nesly\u0161eli je, \u017ee fet\u00e1ln\u00ed bu\u0148ky (bu\u0148ky plodu) sv\u00e9ho d\u00edt\u011bte si v sob\u011b matky nesou a\u017e t\u00e9m\u011b\u0159 30 let po porodu. <\/em><\/p>\n\n\n\n

Jak je to mo\u017en\u00e9?<\/h2>\n\n\n\n

Tento jev se naz\u00fdv\u00e1 mikrochim\u00e9rismus a m\u016f\u017ee b\u00fdt odpov\u011bd\u00ed na ot\u00e1zku, pro\u010d a\u017e 80 % lid\u00ed trp\u00edc\u00edch autoimunitn\u00edm onemocn\u011bn\u00edm jsou \u017eeny, ale i naopak, pro\u010d maj\u00ed \u017eeny, kter\u00e9 rodily, ni\u017e\u0161\u00ed \u0161anci rozvoje rakoviny prsu nebo vaje\u010dn\u00edk\u016f. Mikrochim\u00e9rismus je p\u0159edm\u011btem intenzivn\u00edho v\u011bdeck\u00e9ho zkoum\u00e1n\u00ed a m\u016f\u017ee v\u00fdrazn\u011b zlep\u0161it pochopen\u00ed zdrav\u00ed \u017een.<\/p>\n\n\n\n

Bu\u0148ky jednoho organismu se stanou sou\u010d\u00e1st\u00ed druh\u00e9ho<\/h2>\n\n\n\n

Mikrochim\u00e9rismus zjednodu\u0161en\u011b p\u0159edstavuje proces, p\u0159i n\u011bm\u017e se bu\u0148ky jednoho organismu st\u00e1vaj\u00ed sou\u010d\u00e1st\u00ed druh\u00e9ho organismu. M\u016f\u017ee se vyskytovat po transplantaci kostn\u00ed d\u0159en\u011b, krevn\u00edch transfuz\u00edch nebo u dvoj\u010dat. Ale nej\u010dast\u011bj\u0161\u00ed p\u0159irozenou formou je pr\u00e1v\u011b fet\u00e1ln\u00ed mikrochim\u00e9rismus. <\/p>\n\n\n\n

Bu\u0148ky vyv\u00edjej\u00edc\u00edho se plodu se u\u017e v ran\u00fdch st\u00e1di\u00edch t\u011bhotenstv\u00ed dost\u00e1vaj\u00ed p\u0159es placentu do krevn\u00edho ob\u011bhu matky. To n\u00e1m umo\u017e\u0148uje d\u011blat neinvazivn\u00ed prenat\u00e1ln\u00ed testy z krve matky, p\u0159i nich\u017e je mo\u017en\u00e9 zjistit r\u016fzn\u00e9 zm\u011bny v DNA plodu. Takov\u00e9to fet\u00e1ln\u00ed bu\u0148ky v\u0161ak nez\u016fst\u00e1vaj\u00ed jen v krvi matky, ale n\u011bkter\u00e9 se ukl\u00e1daj\u00ed do r\u016fzn\u00fdch org\u00e1n\u016f a tk\u00e1n\u00ed matky, kde z\u016fst\u00e1vaj\u00ed ulo\u017een\u00e9 i n\u011bkolik des\u00edtek let po porodu. Jedn\u00edm z t\u011bchto org\u00e1n\u016f je i srdce matky.<\/strong><\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Jak\u00fd to v\u0161ak m\u00e1 v\u00fdznam? <\/h2>\n\n\n\n

P\u0159esnou odpov\u011b\u010f na tuto ot\u00e1zku zat\u00edm nezn\u00e1me. Jednou ze zkouman\u00fdch mo\u017enost\u00ed je, \u017ee fet\u00e1ln\u00ed bu\u0148ky m\u011bn\u00ed procesy v t\u011ble matky s c\u00edlem p\u0159esunout \u017eiviny sm\u011brem k plodu. V\u00fdzkumy tak\u00e9 ukazuj\u00ed, \u017ee fet\u00e1ln\u00ed bu\u0148ky mohou pom\u00e1hat \u017eensk\u00e9mu t\u011blu s hojen\u00edm.<\/strong>Po\u0161kozen\u00e1 tk\u00e1\u0148 matky (nap\u0159\u00edklad z porodu nebo po c\u00edsa\u0159sk\u00e9m \u0159ezu) vys\u00edl\u00e1 sign\u00e1ly, kter\u00e9 na toto m\u00edsto p\u0159il\u00e1kaj\u00ed mikrochim\u00e9rick\u00e9 fet\u00e1ln\u00ed bu\u0148ky. Ty dovedou produkovat kolagen a jin\u00e9 faktory, kter\u00e9 urychluj\u00ed hojen\u00ed. Podobn\u011b protektivn\u00ed vliv t\u011bchto bun\u011bk nazna\u010duj\u00ed i studie, kter\u00e9 sledovaly ni\u017e\u0161\u00ed v\u00fdskyt rakoviny prsu \u010di vaje\u010dn\u00edk\u016f u \u017een, kter\u00e9 m\u011bly d\u011bti. Vy\u0161\u0161\u00ed mno\u017estv\u00ed takov\u00fdchto bun\u011bk bylo pozorov\u00e1no tak\u00e9 v n\u00e1dorov\u00e9 tk\u00e1ni u \u017een, kter\u00e9 m\u011bly rakovinu plic i des\u00edtky let po porodu, co\u017e by mohlo vysv\u011btlit jejich lep\u0161\u00ed progn\u00f3zu ve srovn\u00e1n\u00ed se \u017eenami, kter\u00e9 d\u011bti nem\u011bly.<\/p>\n\n\n\n

Na druhou stranu pr\u00e1v\u011b p\u0159\u00edtomnost bun\u011bk plodu v t\u011ble matky i dlouho po porodu m\u016f\u017ee b\u00fdt spojen\u00e1 s \u010dast\u011bj\u0161\u00edm vznikem autoimunitn\u00edch onemocn\u011bn\u00ed u \u017een. <\/strong>Nap\u0159\u00edklad sklerodermie se prim\u00e1rn\u011b vyskytuje u \u017een v poporodn\u00edm v\u011bku. P\u0159\u00edznaky tohoto onemocn\u011bn\u00ed v\u00fdrazn\u011b p\u0159ipom\u00ednaj\u00ed ne\u017e\u00e1douc\u00ed reakci hostitele na darovan\u00fd org\u00e1n (GVHD). U \u017een s t\u00edmto onemocn\u011bn\u00edm byly nalezeny fet\u00e1ln\u00ed bu\u0148ky s chromozomem Y i des\u00edtky let po porodu. Jeliko\u017e se chromozom Y v \u017eensk\u00fdch bu\u0148k\u00e1ch nenach\u00e1z\u00ed, tyto bu\u0148ky poch\u00e1z\u00ed pr\u00e1v\u011b z plodu mu\u017esk\u00e9ho pohlav\u00ed. <\/p>\n\n\n\n

Pouto mezi d\u00edt\u011btem a matkou je velmi siln\u00e9 <\/h2>\n\n\n\n

I kdy\u017e m\u00e1 v\u00fdzkum mikrochim\u00e9rismu p\u0159ed sebou je\u0161t\u011b dlouhou cestu, u\u017e te\u010f je jasn\u00e9, \u017ee mate\u0159stv\u00ed m\u011bn\u00ed \u017eivot \u017een i na t\u00e9 nejmen\u0161\u00ed \u2013 bun\u011b\u010dn\u00e9 \u00farovni<\/strong>. Jestli chcete svou maminku pot\u011b\u0161it a p\u0159ekvapit na Den matek, darujte j\u00ed nap\u0159\u00edklad DNA Health test<\/a>, d\u00edky kter\u00e9mu bude moct zlep\u0161it sv\u016fj \u017eivotn\u00ed styl a celkov\u00e9 zdrav\u00ed. <\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Zdroje:<\/strong><\/p>\n\n\n\n

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  1. Shrivastava, S.; Naik, R.; Suryawanshi, H. a Gupta, N. (2019). Microchimerism: A new concept. Journal of oral and maxillofacial pathology: JOMFP<\/em>, 23<\/em>(2), 311.<\/li>\n\n\n\n
  2. O’Donoghue, K. (2008). Fetal microchimerism and maternal health during and after pregnancy. Obstetric medicine, 1(2), 56\u201364.<\/li>\n\n\n\n
  3. https:\/\/www.smithsonianmag.com\/science-nature\/babys-cells-can-manipulate-moms-body-decades-180956493\/<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    O tom, \u017ee \u017eeny p\u0159ed\u00e1vaj\u00ed sv\u00e9mu d\u00edt\u011bti p\u0159ibli\u017en\u011b 50 % jeho DNA, jste u\u017e jist\u011b sly\u0161eli. M\u00e9n\u011b zn\u00e1m\u00e9, ale ne a\u017e tak p\u0159ekvapiv\u00e9 je, \u017ee bu\u0148ky z t\u011bla matky se v mal\u00e9 m\u00ed\u0159e dost\u00e1vaj\u00ed b\u011bhem jeho v\u00fdvoje do t\u011bla d\u00edt\u011bte. O \u010dem jste v\u0161ak je\u0161t\u011b asi nesly\u0161eli je, \u017ee fet\u00e1ln\u00ed bu\u0148ky (bu\u0148ky plodu) sv\u00e9ho d\u00edt\u011bte […]<\/p>\n","protected":false},"author":6,"featured_media":1372993,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[63],"place-taxonomy":[],"class_list":["post-1372992","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-sk","tag-zaujimavosti"],"acf":[],"views":1972,"_links":{"self":[{"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/posts\/1372992","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/comments?post=1372992"}],"version-history":[{"count":5,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/posts\/1372992\/revisions"}],"predecessor-version":[{"id":1373481,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/posts\/1372992\/revisions\/1373481"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/media\/1372993"}],"wp:attachment":[{"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/media?parent=1372992"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/categories?post=1372992"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/tags?post=1372992"},{"taxonomy":"place-taxonomy","embeddable":true,"href":"https:\/\/dev.dnaera.com\/cs\/wp-json\/wp\/v2\/place-taxonomy?post=1372992"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}